{"product_id":"sv108delivery™","title":"SV108Delivery™ Human NK cell targeted","description":"\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; line-height: 150%; text-align: left;\"\u003e\u003cb\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: black; mso-themecolor: text1;\"\u003eHuman \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eNK cells\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e \u003c\/span\u003e\u003cb\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: black; mso-themecolor: text1;\"\u003etargeted SV108 Delivery\u003csup\u003eTM\u003c\/sup\u003e Kit information and\u003cspan style=\"mso-font-kerning: 0pt; mso-ligatures: none;\"\u003e Supporting Data\u003c\/span\u003e\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; line-height: 150%; text-align: left;\"\u003e \u003c\/p\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; line-height: 150%; text-align: left;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: black; mso-themecolor: text1; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003eTable 1 \u003c\/span\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eThe Characterizations of human NKp46\u003csup\u003e+\u003c\/sup\u003e NK cells targeted LNP-mRNA generated by \u003c\/span\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: black; mso-themecolor: text1;\"\u003eSV108 Delivery\u003csup\u003eTM\u003c\/sup\u003e Kit\u003cspan style=\"mso-font-kerning: 0pt; mso-ligatures: none;\"\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable class=\"MsoNormalTable\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"725\" style=\"width: 507px; border-collapse: collapse; border-image: initial; border: medium none currentcolor;\" height=\"73\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"mso-yfti-irow: 0; mso-yfti-firstrow: yes; height: 24.6pt;\"\u003e\n\u003ctd nowrap style=\"width: 128px; border-width: 1pt medium; border-style: solid none; border-color: windowtext currentcolor; padding: 0in 5.4pt; height: 24.6pt;\"\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd nowrap style=\"width: 107.016px; border-width: 1pt medium; border-style: solid none; border-color: windowtext currentcolor; padding: 0in 5.4pt; height: 24.6pt;\"\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003eEE (%)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd nowrap style=\"width: 106.281px; border-width: 1pt medium; border-style: solid none; border-color: windowtext currentcolor; padding: 0in 5.4pt; height: 24.6pt;\"\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003eSize (nm)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd nowrap style=\"width: 108.141px; border-width: 1pt medium; border-style: solid none; border-color: windowtext currentcolor; padding: 0in 5.4pt; height: 24.6pt;\"\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003ePDI\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"mso-yfti-irow: 1; mso-yfti-lastrow: yes; height: 24.6pt;\"\u003e\n\u003ctd nowrap style=\"width: 128px; border-width: medium medium 1pt; border-style: none none solid; border-color: currentcolor currentcolor windowtext; border-image: initial; padding: 0in 5.4pt; height: 24.6pt;\"\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003eSV108 Delivery\u003csup\u003eTM\u003c\/sup\u003e \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd nowrap style=\"width: 107.016px; border-width: medium medium 1pt; border-style: none none solid; border-color: currentcolor currentcolor windowtext; border-image: initial; padding: 0in 5.4pt; height: 24.6pt;\"\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: black;\"\u003e97.8±2.1\u003c\/span\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd nowrap style=\"width: 106.281px; border-width: medium medium 1pt; border-style: none none solid; border-color: currentcolor currentcolor windowtext; border-image: initial; padding: 0in 5.4pt; height: 24.6pt;\"\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: black;\"\u003e125.8±3.0\u003c\/span\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd nowrap style=\"width: 108.148px; border-width: medium medium 1pt; border-style: none none solid; border-color: currentcolor currentcolor windowtext; border-image: initial; padding: 0in 5.4pt; height: 24.6pt;\"\u003e\n\u003cp class=\"MsoNormal\" align=\"center\" style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; color: black;\"\u003e0.17±0.03\u003c\/span\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\"\u003e \u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eThe kit exhibits consistently high encapsulation efficiency (\u0026gt;95%), generate nanoparticles with a uniform average size of approximately 125 nm, and maintain a low polydispersity index (PDI). \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\"\u003e \u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0759\/1804\/9537\/files\/Table1_SV108.png?v=1778249573\" alt=\"\" width=\"603\" height=\"224\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: 150%;\"\u003e\u003cb\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eFigure 1.\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e Stability of human NKp46\u003csup\u003e+\u003c\/sup\u003e NK cells targeted LNP-mRNA generated by SV108 Delivery\u003csup\u003eTM\u003c\/sup\u003e Kit. The human NKp46\u003csup\u003e+\u003c\/sup\u003e NK cells targeted LNP-mRNA underwent three freeze–thaw cycles. \u003cspan style=\"color: black; mso-themecolor: text1;\"\u003eShown are nanoparticle size (left), polydispersity index (PDI) (right). \u003cspan style=\"mso-spacerun: yes;\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: 150%;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0759\/1804\/9537\/files\/Figure2_SV108.png?v=1778250429\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\" style=\"line-height: 150%;\"\u003e\u003cb\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eFigure 2.\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e \u003c\/span\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eThe SV108 Delivery\u003csup\u003eTM \u003c\/sup\u003ekit demonstrated strong transfection efficacy and cell type specificity in human NK cells. \u003ci\u003eIn vitro \u003c\/i\u003etransfection efficacy: human NK cells were transfected with mRNA encoding eGFP using SV108 Delivery\u003csup\u003eTM\u003c\/sup\u003e kit as indicated. \u003cspan style=\"color: black; mso-themecolor: text1;\"\u003eShown are FACS plots (A) and \u003c\/span\u003eGFP\u003csup\u003e+\u003c\/sup\u003e cells percentage (B) one day post-transfection determined by flow cytometer.\u003c\/span\u003e\u003c\/p\u003e","brand":"SunVax mRNA Therapeutics","offers":[{"title":"SV108 Delivery™ For Human NK Cells delivery of 36μg mRNA","offer_id":48751514452225,"sku":null,"price":639.0,"currency_code":"USD","in_stock":true},{"title":"SV108 Delivery™ For Human NK Cell delivery of 120µg mRNA","offer_id":48751514484993,"sku":null,"price":1439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0759\/1804\/9537\/files\/Small_Kit_without_BG_Bright.png?v=1758050316","url":"https:\/\/order.sunvaxmrna.com\/products\/sv108delivery%e2%84%a2","provider":"SunVax mRNA Therapeutics","version":"1.0","type":"link"}