SV108Delivery™ Human NK cell targeted

Human NK cells targeted SV108 Delivery^TM Kit information and Supporting Data

Table 1 The Characterizations of human NKp46⁺ NK cells targeted LNP-mRNA generated by SV108 Delivery^TM Kit

The kit exhibits consistently high encapsulation efficiency (>95%), generate nanoparticles with a uniform average size of approximately 125 nm, and maintain a low polydispersity index (PDI). 

Figure 1. Stability of human NKp46⁺ NK cells targeted LNP-mRNA generated by SV108 Delivery^TM Kit. The human NKp46⁺ NK cells targeted LNP-mRNA underwent three freeze–thaw cycles. Shown are nanoparticle size (left), polydispersity index (PDI) (right).  

Figure 2. The SV108 Delivery^TM kit demonstrated strong transfection efficacy and cell type specificity in human NK cells. In vitro transfection efficacy: human NK cells were transfected with mRNA encoding eGFP using SV108 Delivery^TM kit as indicated. Shown are FACS plots (A) and GFP⁺ cells percentage (B) one day post-transfection determined by flow cytometer.