{"product_id":"sv106delivery™-1","title":"SV106 Delivery™ Human CD8 T cell targeted","description":"\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eSunVax is a pioneering biotechnology company \u003c\/span\u003e\u003cspan style=\"mso-bookmark: _Hlk206602618;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003elocated\u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"mso-bookmark: _Hlk206602618;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e in the Greater Boston area, specializing in the development of advanced lipid nanoparticle (LNP) delivery systems and self-amplifying mRNA (samRNA) platforms. Leveraging a proprietary library of over one million molecular structures, SunVax has synthesized and screened more than 60,000 ionizable lipids through high-throughput methods. \u003ca name=\"_Hlk206602597\"\u003e\u003c\/a\u003eTo accelerate progress in the mRNA research community, SunVax launched a series of ready-to-use \u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"mso-bookmark: _Hlk206602618;\"\u003e\u003cspan style=\"mso-bookmark: _Hlk206602597;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003emouse\/human \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"mso-bookmark: _Hlk206602618;\"\u003e\u003cspan style=\"mso-bookmark: _Hlk206602597;\"\u003e\u003cb\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eT cell and CD8 T cell \u003c\/span\u003e\u003c\/b\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"mso-bookmark: _Hlk206602618;\"\u003e\u003cspan style=\"mso-bookmark: _Hlk206602597;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003especific delivery LNP kits \u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"mso-bookmark: _Hlk206602618;\"\u003e\u003cspan style=\"mso-bookmark: _Hlk206602597;\"\u003e\u003cspan style=\"font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003efor research use only for proof-of-concept and screening mRNA constructs \u003ci\u003eex vivo \u003c\/i\u003e(in mouse splenic cells, or in human PBMC cells), and \u003ci\u003ein vivo \u003c\/i\u003e(mouse or humanized mouse).\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"mso-bookmark: _Hlk206602618;\"\u003e\u003cmeta charset=\"utf-8\"\u003e \u003cb data-olk-copy-source=\"MessageBody\"\u003eCell-type specificity:\u003c\/b\u003e\u003cspan\u003e Enabling targeted delivery to human CD8 T \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"mso-bookmark: _Hlk206602618;\"\u003e\u003cspan\u003ecells with exceptional selectivity.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"line-height: 150%; tab-stops: 298.15pt; margin: 24.0pt 0in 12.0pt 0in;\" class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; color: black; mso-themecolor: text1;\"\u003eHuman CD8 T cell targeted SV1\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; color: black; mso-themecolor: text1; mso-fareast-language: ZH-CN;\"\u003e06 \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; color: black; mso-themecolor: text1;\"\u003eDelivery\u003csup\u003e™\u003c\/sup\u003e Kits information and\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; color: black; mso-themecolor: text1; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003e Supporting Data\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp style=\"line-height: 150%; tab-stops: 298.15pt; margin: 24.0pt 0in 12.0pt 0in;\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; color: black; mso-themecolor: text1; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003eTable 4 \u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eThe Characterizations of human CD8 T cell targeted LNP-mRNA generated by \u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; color: black; mso-themecolor: text1;\"\u003eSV106Delivery\u003csup\u003e™\u003c\/sup\u003e Kits\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; color: black; mso-themecolor: text1; mso-font-kerning: 0pt; mso-ligatures: none;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ctable style=\"width: 568px; border-collapse: collapse; border: none;\" width=\"725\" cellpadding=\"0\" cellspacing=\"0\" border=\"1\" class=\"MsoNormalTable\" height=\"67\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"mso-yfti-irow: 0; mso-yfti-firstrow: yes; height: 24.6pt;\"\u003e\n\u003ctd style=\"width: 142.852px; border-top: 1pt solid windowtext; border-left: none; border-bottom: 1pt solid windowtext; border-right: none; padding: 0in 5.4pt; height: 24.6pt;\" nowrap width=\"193\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\" align=\"center\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none; mso-fareast-language: ZH-CN;\"\u003e LNP-mRNA \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 122.375px; border-top: 1pt solid windowtext; border-left: none; border-bottom: 1pt solid windowtext; border-right: none; padding: 0in 5.4pt; height: 24.6pt;\" nowrap width=\"178\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\" align=\"center\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none; mso-fareast-language: ZH-CN;\"\u003eEE (%)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 121.375px; border-top: 1pt solid windowtext; border-left: none; border-bottom: 1pt solid windowtext; border-right: none; padding: 0in 5.4pt; height: 24.6pt;\" nowrap width=\"176\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\" align=\"center\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none; mso-fareast-language: ZH-CN;\"\u003eSize (nm)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 123.5px; border-top: 1pt solid windowtext; border-left: none; border-bottom: 1pt solid windowtext; border-right: none; padding: 0in 5.4pt; height: 24.6pt;\" nowrap width=\"178\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\" align=\"center\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none; mso-fareast-language: ZH-CN;\"\u003ePDI\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"mso-yfti-irow: 1; mso-yfti-lastrow: yes; height: 24.6pt;\"\u003e\n\u003ctd style=\"width: 142.852px; border-top: none; border-right: none; border-left: none; border-image: initial; border-bottom: 1pt solid windowtext; padding: 0in 5.4pt; height: 24.6pt;\" nowrap width=\"193\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\" align=\"center\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; mso-font-kerning: 0pt; mso-ligatures: none; mso-fareast-language: ZH-CN;\"\u003eSV106 Delivery™ \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 122.375px; border-top: none; border-right: none; border-left: none; border-image: initial; border-bottom: 1pt solid windowtext; padding: 0in 5.4pt; height: 24.6pt;\" nowrap width=\"178\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\" align=\"center\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; color: black;\"\u003e98.7±0.8\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none; mso-fareast-language: ZH-CN;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 121.375px; border-top: none; border-right: none; border-left: none; border-image: initial; border-bottom: 1pt solid windowtext; padding: 0in 5.4pt; height: 24.6pt;\" nowrap width=\"176\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\" align=\"center\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; color: black;\"\u003e95.4±1.4\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none; mso-fareast-language: ZH-CN;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003ctd style=\"width: 123.5px; border-top: none; border-right: none; border-left: none; border-image: initial; border-bottom: 1pt solid windowtext; padding: 0in 5.4pt; height: 24.6pt;\" nowrap width=\"178\"\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: center; line-height: 150%;\" align=\"center\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; color: black;\"\u003e0.15±0.02\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; color: black; mso-font-kerning: 0pt; mso-ligatures: none; mso-fareast-language: ZH-CN;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eThe kits exhibit excellent encapsulation efficiency, generate nanoparticles with a uniform average size of approximately 1\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003e0\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e0 nm, and maintain a low polydispersity index (PDI).\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0759\/1804\/9537\/files\/SV106-Figure7.png?v=1757435753\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\" class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eFigure \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003e7\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e.\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e Stability of human CD8 T cell targeted LNP-mRNA generated by SV1\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003e06 \u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eDelivery\u003csup\u003e™\u003c\/sup\u003e Kits. The \u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003ehuman CD8 \u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eT cell targeted LNP-mRNA underwent three freeze–thaw cycles prior to transfect mouse\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003e \u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003esplenic cells. \u003cspan style=\"color: black; mso-themecolor: text1;\"\u003eShown are nanoparticle size (A), polydispersity index (PDI) (B), and transfection efficiency in \u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; color: black; mso-themecolor: text1; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003ehuman PBMC\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; color: black; mso-themecolor: text1; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e cells (C).\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\" class=\"MsoNormal\"\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0759\/1804\/9537\/files\/Sv106-Figure8.png?v=1757435753\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\" class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003eFigure \u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003e8\u003c\/span\u003e\u003c\/b\u003e\u003cb\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e.\u003c\/span\u003e\u003c\/b\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e \u003cb\u003eThe SV106 Delivery\u003csup\u003e™\u003c\/sup\u003e kit demonstrated robust transfection efficiency and cell-type specificity in human PBMC cells. \u003c\/b\u003e\u003ci\u003eIn vitro \u003c\/i\u003etransfection efficacy: Human PBMC cells were transfected with LNP–mRNA encoding eGFP, formulated using the SV106Delivery\u003csup\u003e™\u003c\/sup\u003e kit as indicated. Shown are representative FACS plots (\u003cb\u003eA\u003c\/b\u003e) and the percentage of GFP\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Cambria Math',serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bidi-font-family: 'Cambria Math'; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e⁺\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt;\"\u003e cells (\u003cb\u003eB\u003c\/b\u003e) one day post-transfection, as determined by flow cytometry.\u003c\/span\u003e\u003cspan style=\"font-size: 11.0pt; line-height: 150%; font-family: 'Arial',sans-serif; mso-fareast-font-family: DengXian; mso-fareast-theme-font: minor-fareast; mso-bevel-captop-bevelstyle: 0; mso-bevel-captop-dpiwidth: 0pt; mso-bevel-captop-dpiheight: 0pt; mso-bevel-capbot-bevelstyle: 0; mso-bevel-capbot-dpiwidth: 0pt; mso-bevel-capbot-dpiheight: 0pt; mso-bevel-material: 10; mso-bevel-colorextrusion-color: #C00000; mso-bevel-colorextrusion-alpha: 100.0%; mso-bevel-dpiextrusion: 4.5pt; mso-bevel-dpicontour: 0pt; mso-fareast-language: ZH-CN;\"\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"margin-bottom: 0in; text-align: justify; text-justify: inter-ideograph; line-height: 150%; tab-stops: 298.15pt;\" class=\"MsoNormal\"\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStore Temperature\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eLipid Mixture: -80°C\u003c\/p\u003e\n\u003cp\u003eFormulation Buffer: Room Temperature\u003c\/p\u003e\n\u003cp\u003eReagent A: \u003cmeta charset=\"utf-8\"\u003e-80°C\u003c\/p\u003e\n\u003cp\u003eReagent B-6: 4°C\u003c\/p\u003e","brand":"SunVax mRNA Therapeutics","offers":[{"title":"SV106 Delivery™ For Human CD8 T Cells Delivery of 36 μg mRNA (3 x 300μL Lipid Mixture, 1 x 1.5mL Formulation Buffer, 1 x 3mg Reagent A, 1 x 400μL Reagent B-6, Research Use Only)","offer_id":46714797490433,"sku":"SV106-36μg","price":639.0,"currency_code":"USD","in_stock":true},{"title":"SV106 Delivery™ PLUS For Human CD8 T Cell Delivery of 120 μg mRNA (5 x 600μL Lipid Mixture, 2 x 2ml Formulation Buffer, 2 x 3mg Reagent A, 2 x 600μl Reagent B-6, Research Use Only)","offer_id":46714797523201,"sku":"SV106-120μg","price":1439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0759\/1804\/9537\/files\/Small_Kit_without_BG_Bright.png?v=1758050316","url":"https:\/\/order.sunvaxmrna.com\/products\/sv106delivery%e2%84%a2-1","provider":"SunVax mRNA Therapeutics","version":"1.0","type":"link"}